منابع مشابه
Division of Metabolic Disorders, Children’s Hospital of Orange County, Orange, California
Congenital disorders of glycosylation (CDG) arise from pathogenic mutations in over one hundred genes leading to impaired protein or lipid glycosylation. ALG1 encodes a β1,4 mannosyltransferase that catalyzes the addition of the first of nine mannose moieties to form a dolichol-lipid linked oligosaccharide intermediate (DLO) required for proper N-linked glycosylation. ALG1 mutations cause a rar...
متن کاملComposition and distribution of beach debris in Orange County, California.
Many studies have quantified debris collected on beaches around the world. Only a few of those studies have been conducted in the United States, and they are largely limited to semi-quantitative efforts performed as part of volunteer clean-up activities. This study quantifies the distribution and composition of beach debris by sampling 43 stratified random sites on the Orange County, California...
متن کاملThe curious case of the Arctic mastodons.
In 1796, the French anatomist Georges Cuvier sparked widespread interest in the idea that many organisms, including some large mammals, had gone extinct in the recent geologic past (1). He proposed, based on the morphology and function of molars, that African and Indian elephants were separate species and that they were distinct from at least two additional elephants known only from fossils: ta...
متن کاملSpatial and temporal distribution of mosquitoes in underground storm drain systems in Orange County, California.
Underground storm drain systems in urban areas of Orange County include thousands of miles of gutters and underground pipelines, plus hundreds of thousands of catch basins and manhole chambers, all of which drain runoff water from residential, business and commercial establishments as well as highways and streets. These systems serve as major developmental and resting sites for anthropophilic a...
متن کاملAccess to Firearms among Orange County Youth: A School-Based Study
OBJECTIVE School-associated firearm violence among children and adolescents is a national public concern. The objective of this study was to determine the accessibility of firearms, methods of firearm access and firearm safety knowledge among middle and high school students in Orange County, California. METHODS After permission from school officials and parents was obtained, a 24-question sur...
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ژورنال
عنوان ژورنال: Science
سال: 1902
ISSN: 0036-8075,1095-9203
DOI: 10.1126/science.16.408.669